Estimated dead space fraction and the ventilatory ratio at days 1 and 2 were significantly higher among non-survivors ( p < 0.01). Individual patient data from 940 ARDS patients were analyzed. The present study is a post hoc analysis of a prospective observational cohort study of ICUs of two tertiary care hospitals in the Netherlands. This study aimed to compare various methods for dead space estimation and the ventilatory ratio in patients with acute respiratory distress syndrome (ARDS) and to determine their independent values for predicting death at day 30. 45: 227–243.Indirect indices for measuring impaired ventilation, such as the estimated dead space fraction and the ventilatory ratio, have been shown to be independently associated with an increased risk of mortality. The physiologic basis of pulmonary gas exchange: implications for clinical interpretation of arterial blood gases. Philadelphia: Lippincott Williams & Wilkins. In: Lippincott's Pathophysiology Series: Pulmonary Pathophysiology. “Gas transport to and from peripheral tissues”. In: Fishman's Pulmonary Diseases and Disorders, edited by MA, Grippi (editor-in-chief), JA, Elias, JA, Fishman, RM, Kotloff, AI, Pack, RM, Senior (editors). ![]() “Clinical presentations: gas exchange and transport”.
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